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Anthony Didato, DMD Balanced Aesthetics + Wellness Leaky Gut (Intestinal Permeability) and Systemic Inflammation Increased intestinal permeability allows endotoxins (LPS) to enter the bloodstream, triggering systemic inflammatory cascades linked to anxiety, depression, brain fog, Frontiers in Immunology KPV Anti-Inflammatory Tripeptide From Alpha-MSH KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH) with potent anti-inflammatory properties

These studies have shown effects in controlled animal settings but do not directly translate to guaranteed human outcomes

J Urol 2008

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Matrixyl has a robust cosmetic trial record multiple randomized controlled trials confirm statistically significant reductions in wrinkle severity scores compared to placebo at concentrations as low as 0.001%